IVF with PGD Gender Selection in Turkey: Cost Breakdown.

In recent years, Turkey has emerged as a popular destination for couples seeking IVF (In Vitro Fertilization) with PGD (Preimplantation Genetic Diagnosis) for gender selection.

This medical procedure offers the possibility to select the sex of the baby, which can be a critical consideration for some families due to cultural, medical, or personal reasons.

The combination of advanced medical facilities, experienced professionals, and competitive pricing makes Turkey an attractive option for this specialized fertility treatment.

Understanding IVF with PGD for Gender Selection

IVF involves fertilizing an egg outside the human body, in a laboratory setting. PGD is a technique used alongside IVF to screen embryos for genetic conditions and chromosomal abnormalities before they are implanted in the uterus.

When it comes to gender selection, PGD can identify the sex chromosomes of embryos, allowing parents to choose the gender of their baby.

The process begins with ovarian stimulation, where hormones are administered to encourage the production of multiple eggs.

These eggs are then retrieved and fertilized with sperm. The resulting embryos are cultured for a few days, after which a few cells are biopsied from each embryo.

The genetic material from these cells is analyzed to determine the sex and any genetic conditions. Finally, one or more healthy embryos of the desired gender are transferred to the uterus.

Factors Influencing the Cost

Several factors can influence the cost of IVF with PGD for gender selection in Turkey:

Clinic Reputation and Expertise

The reputation and expertise of the clinic and medical team can significantly impact the cost.

Clinics with highly experienced specialists and state-of-the-art facilities may charge higher fees but often provide higher success rates and a better overall experience.

Patient’s Medical History and Requirements

Individual patient factors, such as age, fertility history, and underlying medical conditions, can affect the treatment plan and cost.

Patients with complex medical histories may require more extensive monitoring, additional tests, or specialized treatments, increasing the overall cost.

Number of Cycles Required

While some patients may achieve success in the first IVF cycle, others may require multiple cycles, each incurring additional costs.

The success rate of IVF can vary based on age and other factors, influencing the total number of cycles needed.

Extent of Genetic Testing

The extent and complexity of genetic testing required during PGD can also impact the cost. Some patients may opt for comprehensive genetic screening beyond gender selection, which can increase the overall cost.

Prices of all types of the IVF with PGD for Gender Selection in Turkey.

Standard IVF with PGD for Gender Selection

Definition and Details

Standard IVF with PGD for gender selection is a well-established procedure used to help couples conceive a child of a desired gender.

This process involves several critical stages, beginning with ovarian stimulation, where the female partner receives hormone injections to stimulate the ovaries to produce multiple eggs. This step is crucial as it increases the chances of retrieving a sufficient number of viable eggs for fertilization. Once the eggs are mature, they are retrieved using a minimally invasive surgical procedure under sedation.

The eggs are then fertilized in a controlled laboratory environment using sperm from the male partner or a donor.

After fertilization, the embryos are cultured for several days, typically until they reach the blastocyst stage. During this period, the embryos are closely monitored to assess their development and quality. At the blastocyst stage, a few cells are biopsied from each embryo for genetic analysis.

This is where PGD comes into play, allowing for the detection of chromosomal abnormalities and the determination of the embryos’ sex chromosomes (XX for female and XY for male).

Procedure Steps

Initial Consultation and Pre-Treatment Assessment: Comprehensive medical and fertility history evaluation, physical examination, and preliminary tests such as hormonal assays and ultrasounds.
Ovarian Stimulation: Administration of injectable hormones to stimulate the production of multiple eggs. Regular monitoring through blood tests and ultrasounds to adjust medication dosage.
Egg Retrieval: A minor surgical procedure under sedation to collect mature eggs from the ovaries using a fine needle guided by ultrasound.
Sperm Collection and Preparation: Collection and preparation of sperm from the male partner or a donor, including washing and capacitation.
In Vitro Fertilization (IVF): Fertilization of retrieved eggs with prepared sperm in a laboratory dish, followed by embryo culture for 5-6 days until the blastocyst stage.
PGD Testing: Biopsy of a few cells from each blastocyst to analyze chromosomal makeup and determine the sex of the embryos.
Embryo Transfer: Selection and transfer of embryos of the desired gender into the uterus using a catheter.
Cryopreservation of Extra Embryos: Freezing of any surplus embryos for future use.
Luteal Phase Support: Administration of progesterone or other medications to support the uterine lining and early pregnancy.
Pregnancy Testing and Follow-up: Blood tests to confirm pregnancy, followed by ultrasound scans to monitor early fetal development.

Cost Breakdown

Initial Consultation and Pre-Treatment Assessment: €200 – €400
Ovarian Stimulation and Medication: €1,500 – €3,000
Egg Retrieval and Embryo Culture: €2,500 – €4,000
Sperm Collection and Preparation: €200 – €500
In Vitro Fertilization (IVF): €2,000 – €3,500
PGD Testing: €3,000 – €5,000
Embryo Transfer: €1,000 – €1,500
Cryopreservation of Extra Embryos: €500 – €1,000
Luteal Phase Support: €200 – €500
Pregnancy Testing and Follow-up: €200 – €400

IVF with Comprehensive Chromosomal Screening (CCS) and Gender Selection

Definition and Details

IVF with Comprehensive Chromosomal Screening (CCS) and gender selection is an advanced form of PGD that not only identifies the sex of the embryos but also screens for all chromosomal abnormalities.

CCS, also known as PGS (Preimplantation Genetic Screening), examines the entire set of chromosomes, allowing for the detection of aneuploidies (abnormal number of chromosomes) and structural chromosomal abnormalities.

This type of screening is particularly beneficial for older patients, those with recurrent pregnancy loss, or couples with a history of genetic disorders.

The process begins similarly to standard IVF, with ovarian stimulation and egg retrieval. Once the eggs are fertilized and cultured to the blastocyst stage, a biopsy is taken from each embryo.

The genetic material from these cells undergoes CCS, which provides detailed information about the chromosomal integrity of each embryo.

This level of scrutiny helps identify the healthiest embryos, reducing the risk of miscarriage and genetic disorders.

Procedure Steps

Initial Consultation and Genetic Counseling: Detailed assessment and discussion of genetic risks, family history, and the benefits of CCS.
Ovarian Stimulation: Use of higher doses of gonadotropins for patients with a history of poor ovarian response, accompanied by frequent monitoring.
Egg Retrieval: Performed under sedation with ultrasound guidance; may involve additional steps for patients with specific medical conditions.
Sperm Collection and Preparation: Advanced sperm selection techniques such as ICSI (Intracytoplasmic Sperm Injection) may be used for male factor infertility.
In Vitro Fertilization (IVF): Standard IVF process with an emphasis on achieving high-quality embryos.
Comprehensive Chromosomal Screening (CCS): Detailed analysis of all 23 pairs of chromosomes in each embryo to detect aneuploidies and other abnormalities.
Embryo Transfer: Selection of the healthiest embryos of the desired gender, considering both chromosomal normality and developmental quality.
Cryopreservation of Surplus Embryos: Freezing of additional chromosomally normal embryos for future use.
Luteal Phase Support and Monitoring: Use of progesterone, estrogen, or other medications to support implantation and early pregnancy, along with regular monitoring.
Pregnancy Testing and Genetic Counseling Follow-up: Confirmation of pregnancy and further genetic counseling as needed.

Cost Breakdown

Initial Consultation and Genetic Counseling: €300 – €600
Ovarian Stimulation and Medication: €2,000 – €4,000
Egg Retrieval and Embryo Culture: €3,000 – €4,500
Sperm Collection and Preparation: €300 – €600
In Vitro Fertilization (IVF): €2,500 – €4,000
Comprehensive Chromosomal Screening (CCS): €4,000 – €6,500
Embryo Transfer: €1,200 – €1,800
Cryopreservation of Surplus Embryos: €600 – €1,200
Luteal Phase Support and Monitoring: €300 – €600
Pregnancy Testing and Genetic Counseling Follow-up: €300 – €600

IVF with Single Gene Disorder Testing and Gender Selection

Definition and Details

IVF with Single Gene Disorder Testing and gender selection is designed for couples at risk of passing on a specific genetic disorder to their offspring.

This advanced PGD technique allows for the identification of embryos that carry a particular genetic mutation responsible for a single gene disorder, such as cystic fibrosis, sickle cell anemia, or Huntington’s disease.

In addition to testing for these disorders, the procedure also determines the sex of the embryos, allowing for gender selection.

The procedure begins with the standard IVF process of ovarian stimulation, egg retrieval, and fertilization.

Following fertilization, embryos are cultured until they reach the blastocyst stage. At this point, a biopsy is performed, and the cells are analyzed for the specific genetic mutation associated with the disorder in question.

Procedure Steps

Initial Consultation and Detailed Genetic Counseling: Comprehensive evaluation of family medical history and identification of specific genetic risks.
Ovarian Stimulation and Monitoring: Customized stimulation protocol based on patient’s medical background, with frequent monitoring to adjust medication.
Egg Retrieval: Standard procedure under sedation, with potential use of special techniques if needed for specific medical conditions.
Sperm Collection and Genetic Screening: Collection and preparation of sperm, with potential use of genetic screening for sperm donors if necessary.
In Vitro Fertilization (IVF): Fertilization process with emphasis on obtaining high-quality embryos.
Single Gene Disorder Testing: Precise genetic testing of biopsied cells for the specific disorder, along with gender determination.
Embryo Selection and Transfer: Careful selection of unaffected embryos of the desired gender, considering both genetic and developmental quality.
Cryopreservation of Additional Embryos: Freezing of unaffected embryos for potential future use.
Luteal Phase Support and Medical Follow-up: Support with medications and regular follow-up to monitor implantation and early pregnancy.
Pregnancy Confirmation and Extended Genetic Counseling: Ongoing genetic counseling and support throughout pregnancy and beyond.

Cost Breakdown

Initial Consultation and Genetic Counseling: €500 – €800
Ovarian Stimulation and Medication: €2,500 – €5,000
Egg Retrieval and Embryo Culture: €3,500 – €5,500
Sperm Collection and Genetic Screening: €400 – €800
In Vitro Fertilization (IVF): €3,000 – €5,000
Single Gene Disorder Testing: €5,000 – €8,000
Embryo Transfer: €1,500 – €2,000
Cryopreservation of Additional Embryos: €800 – €1,500
Luteal Phase Support and Medical Follow-up: €400 – €800
Pregnancy Confirmation and Extended Genetic Counseling: €400 – €800

IVF with HLA Matching and Gender Selection

Definition and Details

IVF with HLA (Human Leukocyte Antigen) Matching and gender selection is a specialized procedure aimed at helping families in need of a genetic match for an existing child requiring stem cell transplantation.

This process involves selecting embryos that are not only free from genetic disorders but also match the HLA type of an affected sibling, which can be crucial for conditions like leukemia or other hematological disorders. In addition to HLA matching, this process also allows for gender selection.

The IVF process for HLA matching involves ovarian stimulation, egg retrieval, and fertilization, followed by embryo culture. During the biopsy, cells are analyzed for HLA compatibility and gender determination.

Procedure Steps

Initial Consultation and Comprehensive Genetic Counseling: Detailed evaluation of the family’s medical history, HLA matching requirements, and ethical considerations.
Ovarian Stimulation and Monitoring: Customized protocol to maximize the number of high-quality eggs, with close monitoring.
Egg Retrieval: Standard surgical procedure with sedation, ensuring minimal discomfort and optimal egg retrieval.
Sperm Collection and Preparation: Use of donor sperm if necessary, with HLA testing for compatibility.
In Vitro Fertilization (IVF): Fertilization of eggs, with emphasis on creating a sufficient number of embryos for HLA and genetic testing.
HLA Matching and Genetic Testing: Biopsy of embryos to determine HLA compatibility and gender, as well as screening for genetic disorders.
Embryo Selection and Transfer: Careful selection of HLA-matched, healthy, and desired gender embryos for transfer.
Cryopreservation of Matched Embryos: Freezing of additional HLA-matched embryos for potential future use.
Luteal Phase Support and Monitoring: Use of hormonal support to aid implantation and early pregnancy, with regular follow-up appointments.
Pregnancy Confirmation and Specialized Medical Support: Ongoing monitoring and support, including preparation for potential medical procedures for the existing child.

Cost Breakdown

Initial Consultation and Genetic Counseling: €600 – €1,000
Ovarian Stimulation and Medication: €3,000 – €6,000
Egg Retrieval and Embryo Culture: €4,000 – €6,500
Sperm Collection and HLA Testing: €500 – €1,000
In Vitro Fertilization (IVF): €3,500 – €6,000
HLA Matching and Genetic Testing: €6,000 – €10,000
Embryo Transfer: €1,800 – €2,500
Cryopreservation of Matched Embryos: €1,000 – €1,800
Luteal Phase Support and Monitoring: €500 – €1,000
Pregnancy Confirmation and Specialized Medical Support: €600 – €1,200

IVF with Expanded Carrier Screening and Gender Selection

Definition and Details

IVF with Expanded Carrier Screening (ECS) and gender selection is an advanced reproductive option for couples who want to ensure their child is free from a wide range of genetic disorders, while also choosing the gender of their baby.

Expanded Carrier Screening involves testing prospective parents for hundreds of genetic mutations that could potentially be passed on to their offspring.

This comprehensive screening helps identify carrier status for numerous conditions, ranging from common disorders like cystic fibrosis to rare diseases like Gaucher disease.

The process begins with the usual IVF steps: ovarian stimulation, egg retrieval, and fertilization. However, before the embryos are created, both partners undergo ECS to identify any genetic mutations they may carry.

Procedure Steps

Initial Consultation and Expanded Carrier Screening (ECS): Comprehensive assessment of both partners, including ECS to identify carrier status for a wide range of genetic conditions.
Ovarian Stimulation and Individualized Medication Protocol: Tailored medication regimen to maximize egg production, monitored through regular tests and ultrasounds.
Egg Retrieval: Outpatient surgical procedure under sedation, with a focus on retrieving a maximum number of eggs.
Sperm Collection and Screening: Collection and screening of sperm for genetic mutations, if necessary.
In Vitro Fertilization (IVF): Standard IVF procedure, with careful handling and culture of embryos to the blastocyst stage.
Preimplantation Genetic Testing (PGT): Genetic analysis of biopsied cells from embryos to check for identified genetic mutations, chromosomal status, and gender.
Embryo Selection and Transfer: Selection of genetically normal embryos that do not carry identified mutations and are of the desired gender.
Cryopreservation of Additional Embryos: Freezing of unaffected embryos for potential future use.
Luteal Phase Support and Ongoing Monitoring: Administration of medications to support the uterine lining and monitoring through pregnancy tests and early scans.
Pregnancy Confirmation and Post-Transfer Counseling: Confirmation of pregnancy and continued counseling to manage any concerns or questions.

Cost Breakdown

Initial Consultation and Expanded Carrier Screening (ECS): €800 – €1,200
Ovarian Stimulation and Medication: €3,500 – €6,500
Egg Retrieval and Embryo Culture: €4,500 – €7,000
Sperm Collection and Genetic Screening: €600 – €1,200
In Vitro Fertilization (IVF): €4,000 – €6,500
Preimplantation Genetic Testing (PGT): €6,500 – €10,000
Embryo Transfer: €2,000 – €2,800
Cryopreservation of Additional Embryos: €1,200 – €2,000
Luteal Phase Support and Monitoring: €600 – €1,200
Pregnancy Confirmation and Post-Transfer Counseling: €800 – €1,200

IVF with Mitochondrial Replacement Therapy (MRT) and Gender Selection

Definition and Details

IVF with Mitochondrial Replacement Therapy (MRT) and gender selection is an advanced technique designed for women with mitochondrial DNA disorders.

Mitochondria, often referred to as the “powerhouses” of cells, are inherited from the mother and contain their own DNA. Mutations in mitochondrial DNA can lead to serious health conditions.

MRT involves replacing defective mitochondria with healthy ones from a donor egg, ensuring the resulting child does not inherit the mitochondrial disorder.

This procedure is also known as “three-parent IVF” because the child inherits genetic material from three individuals: the nuclear DNA from the biological parents and mitochondrial DNA from the donor.

The MRT process begins with standard IVF procedures, including ovarian stimulation and egg retrieval from the mother.

A donor egg with healthy mitochondria is also retrieved. The nuclear DNA from the mother’s egg is transferred to the donor egg, which has had its nuclear DNA removed, leaving only the healthy mitochondria.

Procedure Steps

Initial Consultation and Genetic Counseling: Detailed review of family history and genetic risks, including the implications of MRT.
Ovarian Stimulation and Monitoring: Customized hormone regimen to stimulate the ovaries for maximum egg production, with regular monitoring.
Egg Retrieval from Mother and Donor: Retrieval of eggs from the mother and a mitochondrial donor, performed under sedation.
Mitochondrial Replacement and Nuclear Transfer: Removal of nuclear DNA from the donor egg and transfer of the mother’s nuclear DNA, creating a healthy egg with donor mitochondria.
In Vitro Fertilization (IVF): Fertilization of the reconstructed egg with sperm from the male partner, followed by embryo culture.
Preimplantation Genetic Testing (PGT): Testing of embryos for mitochondrial integrity, chromosomal status, and gender determination.
Embryo Selection and Transfer: Selection of embryos free from mitochondrial mutations, chromosomally normal, and of the desired gender.
Cryopreservation of Additional Embryos: Freezing of any viable embryos not selected for immediate transfer.
Luteal Phase Support and Medical Monitoring: Administration of hormonal support and regular follow-up for implantation and early pregnancy.
Pregnancy Confirmation and Continued Support: Confirmation of pregnancy and ongoing monitoring, with specialized support as needed.

Cost Breakdown

Initial Consultation and Genetic Counseling: €1,000 – €1,500
Ovarian Stimulation and Medication: €4,000 – €7,000
Egg Retrieval from Mother and Donor: €6,000 – €10,000
Mitochondrial Replacement and Nuclear Transfer: €8,000 – €15,000
In Vitro Fertilization (IVF): €5,000 – €8,000
Preimplantation Genetic Testing (PGT): €7,000 – €12,000
Embryo Transfer: €2,500 – €3,500
Cryopreservation of Additional Embryos: €1,500 – €2,500
Luteal Phase Support and Monitoring: €800 – €1,500
Pregnancy Confirmation and Continued Support: €1,000 – €1,500

IVF with Preimplantation Genetic Diagnosis (PGD) for Monogenic Disorders and Gender Selection

Definition and Details

IVF with Preimplantation Genetic Diagnosis (PGD) for Monogenic Disorders and gender selection is a highly specialized procedure aimed at couples who carry specific genetic mutations for single-gene disorders, such as Tay-Sachs disease, Marfan syndrome, or hemophilia.

This process allows for the detection of these monogenic disorders in embryos before implantation, ensuring that only unaffected embryos are transferred. In addition, the procedure offers the option of selecting the gender of the child.

The procedure begins with ovarian stimulation and egg retrieval, followed by fertilization and embryo culture.

Once the embryos reach the blastocyst stage, a biopsy is performed to extract a few cells for genetic analysis.

PGD testing identifies embryos carrying the specific genetic mutations associated with the monogenic disorder. This precise genetic testing helps differentiate between affected, carrier, and unaffected embryos.

Embryos that are free from the genetic disorder and of the desired gender are selected for transfer. The process is especially beneficial for couples with a known risk of transmitting a serious genetic condition to their offspring.

The procedure involves extensive genetic counseling to ensure that the couple understands the implications of the genetic testing and the potential outcomes. This level of genetic screening provides peace of mind for parents concerned about the health and wellbeing of their future children.

Procedure Steps

Initial Consultation and Genetic Counseling: Comprehensive evaluation of genetic risks and discussion of the specific monogenic disorder.
Ovarian Stimulation and Monitoring: Customized hormonal regimen to maximize egg yield, with frequent monitoring to optimize outcomes.
Egg Retrieval: Surgical procedure under sedation to collect mature eggs, with careful handling to ensure viability.
Sperm Collection and Preparation: Collection of sperm from the male partner or donor, with preparation for fertilization.
In Vitro Fertilization (IVF): Fertilization of eggs and culture of embryos to the blastocyst stage, with monitoring for development.
Preimplantation Genetic Diagnosis (PGD): Genetic testing of biopsied cells to detect monogenic disorders and determine chromosomal status and gender.
Embryo Selection and Transfer: Selection of embryos free from the monogenic disorder and of the desired gender for transfer.
Cryopreservation of Additional Embryos: Freezing of unaffected embryos for future use.
Luteal Phase Support and Medical Follow-up: Administration of hormonal support and regular follow-up for implantation and early pregnancy monitoring.
Pregnancy Confirmation and Genetic Counseling Continuation: Confirmation of pregnancy and ongoing genetic counseling as needed.

Cost Breakdown

Initial Consultation and Genetic Counseling: €700 – €1,200
Ovarian Stimulation and Medication: €3,500 – €6,500
Egg Retrieval and Embryo Culture: €4,000 – €6,500
Sperm Collection and Preparation: €600 – €1,000
In Vitro Fertilization (IVF): €4,000 – €7,000
Preimplantation Genetic Diagnosis (PGD): €5,000 – €8,000
Embryo Transfer: €2,000 – €2,800
Cryopreservation of Additional Embryos: €1,200 – €2,000
Luteal Phase Support and Monitoring: €600 – €1,200
Pregnancy Confirmation and Genetic Counseling Continuation: €800 – €1,200

IVF with Advanced Maternal Age Considerations and Gender Selection

Definition and Details

IVF with Advanced Maternal Age Considerations and gender selection is tailored specifically for women of advanced maternal age, typically defined as women over the age of 35.

As maternal age increases, the quality and quantity of eggs decrease, leading to a higher risk of chromosomal abnormalities and reduced fertility.

This type of IVF incorporates advanced reproductive technologies and strategies to maximize the chances of conception, while also allowing for gender selection.

Procedure Steps

Initial Consultation and Ovarian Reserve Testing: Detailed evaluation of ovarian reserve and fertility potential, including hormone assays and ultrasound.
Customized Ovarian Stimulation Protocol: High-dose gonadotropin stimulation tailored to maximize egg yield, with regular monitoring.
Egg Retrieval: Outpatient procedure under sedation, with careful handling to preserve egg quality.
Sperm Collection and Intracytoplasmic Sperm Injection (ICSI): Collection of sperm and use of ICSI to fertilize eggs, especially useful for male factor infertility.
In Vitro Fertilization (IVF): Culture of fertilized eggs to the blastocyst stage, with close monitoring of embryo development.
Preimplantation Genetic Testing for Aneuploidy (PGT-A): Comprehensive chromosomal screening to identify normal embryos, along with gender determination.
Embryo Selection and Transfer: Transfer of chromosomally normal embryos of the desired gender, selected based on quality and developmental potential.
Cryopreservation of Surplus Embryos: Freezing of additional healthy embryos for future attempts.
Luteal Phase Support and Ongoing Monitoring: Hormonal support and regular check-ups to support early pregnancy.
Pregnancy Confirmation and Support: Confirmation of pregnancy and continued support, with additional screening if necessary due to maternal age.

Cost Breakdown

Initial Consultation and Ovarian Reserve Testing: €800 – €1,300
Customized Ovarian Stimulation Protocol: €4,000 – €7,500
Egg Retrieval and Embryo Culture: €4,500 – €7,500
Sperm Collection and ICSI: €700 – €1,200
In Vitro Fertilization (IVF): €4,500 – €7,500
Preimplantation Genetic Testing for Aneuploidy (PGT-A): €6,000 – €10,000
Embryo Transfer: €2,500 – €3,500
Cryopreservation of Surplus Embryos: €1,500 – €2,500
Luteal Phase Support and Monitoring: €700 – €1,200
Pregnancy Confirmation and Support: €800 – €1,300

IVF with Preimplantation Genetic Diagnosis (PGD) for Translocations and Gender Selection

Definition and Details

IVF with Preimplantation Genetic Diagnosis (PGD) for Translocations and gender selection is a specialized procedure designed for couples where one or both partners carry a chromosomal translocation. Translocations are structural changes in chromosomes where parts of chromosomes are rearranged.

They can be balanced (where no genetic material is gained or lost) or unbalanced (where there is an abnormal amount of genetic material).

While balanced translocations may not affect the carrier’s health, they can lead to infertility, recurrent miscarriages, or the birth of children with genetic disorders due to unbalanced translocations.

Procedure Steps

Initial Consultation and Genetic Counseling: Detailed review of family history and genetic risks associated with chromosomal translocations.
Ovarian Stimulation and Monitoring: Personalized hormone regimen to stimulate the ovaries for maximum egg production, with frequent monitoring.
Egg Retrieval: Surgical procedure to collect eggs from the ovaries, performed under sedation.
Sperm Collection and Fertilization: Collection and preparation of sperm, followed by fertilization of eggs and embryo culture.
Preimplantation Genetic Diagnosis (PGD): Genetic testing to detect translocations and chromosomal status, including gender determination.
Embryo Selection and Transfer: Selection of embryos without chromosomal translocations and of the desired gender for transfer.
Cryopreservation of Additional Embryos: Freezing of any viable embryos not selected for immediate transfer.
Luteal Phase Support and Medical Monitoring: Administration of hormonal support and regular follow-up for implantation and early pregnancy.
Pregnancy Confirmation and Continued Support: Confirmation of pregnancy and ongoing monitoring, with specialized support as needed.

Cost Breakdown

Initial Consultation and Genetic Counseling: €900 – €1,400
Ovarian Stimulation and Medication: €4,200 – €7,200
Egg Retrieval and Embryo Culture: €5,000 – €8,000
Sperm Collection and Preparation: €700 – €1,100
Preimplantation Genetic Diagnosis (PGD): €7,000 – €11,000
Embryo Transfer: €2,500 – €3,500
Cryopreservation of Additional Embryos: €1,600 – €2,400
Luteal Phase Support and Monitoring: €700 – €1,300
Pregnancy Confirmation and Continued Support: €1,000 – €1,500

IVF with Preimplantation Genetic Screening (PGS) and Gender Selection

Definition and Details

IVF with Preimplantation Genetic Screening (PGS) and gender selection is a procedure aimed at increasing the success rate of IVF by screening embryos for chromosomal normalcy before implantation.

PGS, also known as Preimplantation Genetic Testing for Aneuploidy (PGT-A), identifies embryos with the correct number of chromosomes, which is crucial for avoiding implantation failure, miscarriage, or the birth of a child with chromosomal abnormalities such as Down syndrome.

The process starts with ovarian stimulation and egg retrieval, followed by fertilization and embryo culture.

At the blastocyst stage, a biopsy is performed to remove a few cells from each embryo. These cells are analyzed to determine the chromosomal status of the embryos.

PGS can detect aneuploidies (abnormal number of chromosomes) and select embryos that are euploid (normal chromosomal number).

Additionally, PGS provides the opportunity for gender selection based on the couple’s preference.

Procedure Steps

Initial Consultation and Genetic Counseling: In-depth discussion of genetic risks, family history, and the benefits of PGS.
Ovarian Stimulation and Monitoring: Tailored hormone therapy to stimulate the ovaries, with regular ultrasounds and blood tests.
Egg Retrieval: Surgical procedure to collect mature eggs from the ovaries under sedation.
Sperm Collection and Fertilization: Collection of sperm and fertilization of eggs in the lab, with embryo culture to the blastocyst stage.
Preimplantation Genetic Screening (PGS): Biopsy and chromosomal analysis of embryos to identify euploid and aneuploid embryos, and determine gender.
Embryo Selection and Transfer: Transfer of euploid embryos of the desired gender to the uterus.
Cryopreservation of Additional Embryos: Freezing of any surplus euploid embryos for future use.
Luteal Phase Support and Monitoring: Administration of progesterone and other medications to support the uterine lining and implantation.
Pregnancy Confirmation and Monitoring: Pregnancy test and ongoing monitoring for early pregnancy support and care.

Cost Breakdown

Initial Consultation and Genetic Counseling: €1,000 – €1,500
Ovarian Stimulation and Medication: €4,500 – €8,000
Egg Retrieval and Embryo Culture: €5,500 – €9,000
Sperm Collection and Preparation: €800 – €1,200
Preimplantation Genetic Screening (PGS): €7,500 – €12,000
Embryo Transfer: €2,800 – €3,800
Cryopreservation of Additional Embryos: €1,800 – €2,800
Luteal Phase Support and Monitoring: €800 – €1,400
Pregnancy Confirmation and Monitoring: €1,200 – €1,800

Comparing Costs Across Major Cities in Turkey

The cost of IVF with PGD for gender selection can vary significantly across different cities in Turkey, primarily due to differences in living costs, clinic reputation, and the availability of specialized services. Here’s a comparative overview of costs in three major cities:

Istanbul

As Turkey’s largest city and a major medical tourism hub, Istanbul offers a wide range of clinics with varying levels of expertise and pricing.

The cost of IVF with PGD in Istanbul generally ranges from €9,000 to €18,000. The city’s international reputation and access to top-tier medical facilities contribute to higher prices.

Ankara

The capital city, Ankara, provides a mix of public and private healthcare facilities. The cost here is slightly lower compared to Istanbul, typically ranging from €8,500 to €16,500.

Ankara offers high-quality medical care with experienced professionals, often at more affordable rates.

Izmir

Izmir, known for its beautiful coastline and medical tourism infrastructure, offers competitive pricing for IVF with PGD. The cost in Izmir ranges from €8,000 to €15,000, making it an attractive option for patients looking for high-quality care at a more affordable price.

Prices of IVF PGD with Gender Selection in Istanbul, Ankara, and Izmir.

Conventional IVF with PGD for Gender Selection

Istanbul

Initial Consultation and Testing: €800 – €1,200
Ovarian Stimulation and Medication: €4,200 – €6,800
Egg Retrieval and Embryo Culture: €5,000 – €7,000
Sperm Collection and ICSI: €1,000 – €1,500
PGD for Gender Selection: €6,500 – €9,500
Embryo Transfer: €2,500 – €3,000
Cryopreservation of Additional Embryos: €1,500 – €2,200
Luteal Phase Support: €700 – €1,000
Pregnancy Confirmation: €800 – €1,200
Total Cost in Istanbul: €22,000 – €33,400

Ankara

Initial Consultation and Testing: €700 – €1,100
Ovarian Stimulation and Medication: €3,800 – €6,500
Egg Retrieval and Embryo Culture: €4,500 – €6,500
Sperm Collection and ICSI: €900 – €1,400
PGD for Gender Selection: €6,000 – €9,000
Embryo Transfer: €2,300 – €2,800
Cryopreservation of Additional Embryos: €1,300 – €2,000
Luteal Phase Support: €600 – €900
Pregnancy Confirmation: €700 – €1,000
Total Cost in Ankara: €20,800 – €31,200

Izmir

Initial Consultation and Testing: €750 – €1,150
Ovarian Stimulation and Medication: €4,000 – €6,700
Egg Retrieval and Embryo Culture: €4,800 – €6,800
Sperm Collection and ICSI: €950 – €1,450
PGD for Gender Selection: €6,200 – €9,200
Embryo Transfer: €2,400 – €2,900
Cryopreservation of Additional Embryos: €1,400 – €2,100
Luteal Phase Support: €650 – €950
Pregnancy Confirmation: €750 – €1,050
Total Cost in Izmir: €21,200 – €32,300

IVF with Egg Donation and PGD for Gender Selection

Istanbul

Initial Consultation and Donor Matching: €1,500 – €2,200
Donor Stimulation and Medication: €4,800 – €7,500
Egg Retrieval and Embryo Culture: €5,500 – €8,000
Sperm Collection and ICSI: €1,200 – €1,800
PGD for Gender Selection: €6,800 – €9,800
Embryo Transfer: €2,700 – €3,200
Cryopreservation of Additional Embryos: €1,600 – €2,300
Luteal Phase Support: €800 – €1,200
Pregnancy Confirmation: €900 – €1,300
Total Cost in Istanbul: €25,800 – €37,300

Ankara

Initial Consultation and Donor Matching: €1,300 – €2,000
Donor Stimulation and Medication: €4,500 – €7,000
Egg Retrieval and Embryo Culture: €5,000 – €7,500
Sperm Collection and ICSI: €1,100 – €1,700
PGD for Gender Selection: €6,500 – €9,500
Embryo Transfer: €2,500 – €3,000
Cryopreservation of Additional Embryos: €1,500 – €2,200
Luteal Phase Support: €700 – €1,100
Pregnancy Confirmation: €800 – €1,200
Total Cost in Ankara: €24,400 – €35,200

Izmir

Initial Consultation and Donor Matching: €1,400 – €2,100
Donor Stimulation and Medication: €4,600 – €7,200
Egg Retrieval and Embryo Culture: €5,200 – €7,700
Sperm Collection and ICSI: €1,150 – €1,750
PGD for Gender Selection: €6,600 – €9,600
Embryo Transfer: €2,600 – €3,100
Cryopreservation of Additional Embryos: €1,550 – €2,300
Luteal Phase Support: €750 – €1,150
Pregnancy Confirmation: €850 – €1,250
Total Cost in Izmir: €25,000 – €36,150

IVF with Sperm Donation and PGD for Gender Selection

Istanbul

Initial Consultation and Donor Matching: €1,200 – €1,700
Ovarian Stimulation and Medication: €4,500 – €7,000
Egg Retrieval and Embryo Culture: €5,300 – €7,500
Sperm Donation and ICSI: €1,500 – €2,000
PGD for Gender Selection: €6,700 – €9,500
Embryo Transfer: €2,600 – €3,100
Cryopreservation of Additional Embryos: €1,500 – €2,200
Luteal Phase Support: €800 – €1,200
Pregnancy Confirmation: €900 – €1,300
Total Cost in Istanbul: €24,200 – €35,300

Ankara

Initial Consultation and Donor Matching: €1,000 – €1,500
Ovarian Stimulation and Medication: €4,200 – €6,800
Egg Retrieval and Embryo Culture: €4,800 – €7,000
Sperm Donation and ICSI: €1,300 – €1,800
PGD for Gender Selection: €6,500 – €9,000
Embryo Transfer: €2,400 – €2,900
Cryopreservation of Additional Embryos: €1,400 – €2,100
Luteal Phase Support: €700 – €1,000
Pregnancy Confirmation: €800 – €1,100
Total Cost in Ankara: €23,100 – €32,900

Izmir

Initial Consultation and Donor Matching: €1,100 – €1,600
Ovarian Stimulation and Medication: €4,300 – €6,900
Egg Retrieval and Embryo Culture: €5,000 – €7,200
Sperm Donation and ICSI: €1,400 – €1,900
PGD for Gender Selection: €6,600 – €9,200
Embryo Transfer: €2,500 – €3,000
Cryopreservation of Additional Embryos: €1,500 – €2,200
Luteal Phase Support: €750 – €1,100
Pregnancy Confirmation: €850 – €1,200
Total Cost in Izmir: €23,900 – €34,300

IVF with PGS and Gender Selection

Istanbul

Initial Consultation and Genetic Counseling: €1,000 – €1,400
Ovarian Stimulation and Medication: €4,600 – €7,500
Egg Retrieval and Embryo Culture: €5,500 – €8,200
Sperm Collection and ICSI: €1,200 – €1,800
Preimplantation Genetic Screening (PGS): €7,500 – €11,000
Embryo Transfer: €2,700 – €3,300
Cryopreservation of Additional Embryos: €1,600 – €2,400
Luteal Phase Support: €800 – €1,200
Pregnancy Confirmation: €900 – €1,400
Total Cost in Istanbul: €25,800 – €37,800

Ankara

Initial Consultation and Genetic Counseling: €900 – €1,300
Ovarian Stimulation and Medication: €4,200 – €6,800
Egg Retrieval and Embryo Culture: €5,000 – €7,500
Sperm Collection and ICSI: €1,100 – €1,700
Preimplantation Genetic Screening (PGS): €7,000 – €10,500
Embryo Transfer: €2,500 – €3,000
Cryopreservation of Additional Embryos: €1,500 – €2,200
Luteal Phase Support: €700 – €1,100
Pregnancy Confirmation: €800 – €1,200
Total Cost in Ankara: €23,700 – €34,300

Izmir

Initial Consultation and Genetic Counseling: €950 – €1,350
Ovarian Stimulation and Medication: €4,300 – €7,000
Egg Retrieval and Embryo Culture: €5,200 – €7,700
Sperm Collection and ICSI: €1,150 – €1,750
Preimplantation Genetic Screening (PGS): €7,200 – €10,800
Embryo Transfer: €2,600 – €3,100
Cryopreservation of Additional Embryos: €1,550 – €2,300
Luteal Phase Support: €750 – €1,150
Pregnancy Confirmation: €850 – €1,300
Total Cost in Izmir: €24,550 – €35,450

IVF with PGD for Single Gene Disorders and Gender Selection

Istanbul

Initial Consultation and Genetic Counseling: €1,200 – €1,800
Ovarian Stimulation and Medication: €4,800 – €7,800
Egg Retrieval and Embryo Culture: €5,800 – €8,500
Sperm Collection and ICSI: €1,300 – €1,900
PGD for Single Gene Disorders and Gender Selection: €8,000 – €12,000
Embryo Transfer: €2,900 – €3,500
Cryopreservation of Additional Embryos: €1,700 – €2,500
Luteal Phase Support: €900 – €1,300
Pregnancy Confirmation: €1,000 – €1,500
Total Cost in Istanbul: €27,600 – €40,800

Ankara

Initial Consultation and Genetic Counseling: €1,000 – €1,600
Ovarian Stimulation and Medication: €4,400 – €7,200
Egg Retrieval and Embryo Culture: €5,200 – €7,800
Sperm Collection and ICSI: €1,200 – €1,800
PGD for Single Gene Disorders and Gender Selection: €7,500 – €11,000
Embryo Transfer: €2,600 – €3,200
Cryopreservation of Additional Embryos: €1,600 – €2,300
Luteal Phase Support: €800 – €1,200
Pregnancy Confirmation: €900 – €1,400
Total Cost in Ankara: €25,200 – €36,500

Izmir

Initial Consultation and Genetic Counseling: €1,100 – €1,700
Ovarian Stimulation and Medication: €4,500 – €7,500
Egg Retrieval and Embryo Culture: €5,400 – €8,100
Sperm Collection and ICSI: €1,250 – €1,850
PGD for Single Gene Disorders and Gender Selection: €7,800 – €11,500
Embryo Transfer: €2,700 – €3,300
Cryopreservation of Additional Embryos: €1,650 – €2,400
Luteal Phase Support: €850 – €1,250
Pregnancy Confirmation: €950 – €1,400
Total Cost in Izmir: €26,200 – €38,000

IVF with PGD for Chromosomal Disorders and Gender Selection

Istanbul

Initial Consultation and Genetic Counseling: €1,100 – €1,700
Ovarian Stimulation and Medication: €4,700 – €7,600
Egg Retrieval and Embryo Culture: €5,600 – €8,300
Sperm Collection and ICSI: €1,250 – €1,850
PGD for Chromosomal Disorders and Gender Selection: €7,800 – €11,200
Embryo Transfer: €2,800 – €3,400
Cryopreservation of Additional Embryos: €1,600 – €2,400
Luteal Phase Support: €850 – €1,250
Pregnancy Confirmation: €900 – €1,300
Total Cost in Istanbul: €26,600 – €38,900

Ankara

Initial Consultation and Genetic Counseling: €1,000 – €1,500
Ovarian Stimulation and Medication: €4,300 – €7,000
Egg Retrieval and Embryo Culture: €5,100 – €7,700
Sperm Collection and ICSI: €1,150 – €1,750
PGD for Chromosomal Disorders and Gender Selection: €7,300 – €10,800
Embryo Transfer: €2,600 – €3,100
Cryopreservation of Additional Embryos: €1,500 – €2,200
Luteal Phase Support: €800 – €1,100
Pregnancy Confirmation: €850 – €1,300
Total Cost in Ankara: €24,600 – €36,500

Izmir

Initial Consultation and Genetic Counseling: €1,050 – €1,600
Ovarian Stimulation and Medication: €4,400 – €7,200
Egg Retrieval and Embryo Culture: €5,300 – €8,000
Sperm Collection and ICSI: €1,200 – €1,800
PGD for Chromosomal Disorders and Gender Selection: €7,500 – €11,000
Embryo Transfer: €2,700 – €3,300
Cryopreservation of Additional Embryos: €1,550 – €2,300
Luteal Phase Support: €850 – €1,200
Pregnancy Confirmation: €900 – €1,400
Total Cost in Izmir: €25,450 – €37,800

IVF with PGD for Gender Selection and HLA Matching

Istanbul

Initial Consultation and Genetic Counseling: €1,400 – €2,000
Ovarian Stimulation and Medication: €4,900 – €8,200
Egg Retrieval and Embryo Culture: €5,900 – €8,600
Sperm Collection and ICSI: €1,400 – €2,000
PGD for Gender Selection and HLA Matching: €8,200 – €12,500
Embryo Transfer: €3,000 – €3,600
Cryopreservation of Additional Embryos: €1,700 – €2,500
Luteal Phase Support: €900 – €1,300
Pregnancy Confirmation: €1,000 – €1,500
Total Cost in Istanbul: €28,400 – €42,200

Ankara

Initial Consultation and Genetic Counseling: €1,200 – €1,800
Ovarian Stimulation and Medication: €4,500 – €7,500
Egg Retrieval and Embryo Culture: €5,300 – €8,000
Sperm Collection and ICSI: €1,300 – €1,900
PGD for Gender Selection and HLA Matching: €7,800 – €11,800
Embryo Transfer: €2,800 – €3,400
Cryopreservation of Additional Embryos: €1,600 – €2,300
Luteal Phase Support: €800 – €1,200
Pregnancy Confirmation: €900 – €1,400
Total Cost in Ankara: €25,800 – €38,800

Izmir

Initial Consultation and Genetic Counseling: €1,300 – €1,900
Ovarian Stimulation and Medication: €4,600 – €7,700
Egg Retrieval and Embryo Culture: €5,500 – €8,300
Sperm Collection and ICSI: €1,350 – €1,950
PGD for Gender Selection and HLA Matching: €8,000 – €12,000
Embryo Transfer: €2,900 – €3,500
Cryopreservation of Additional Embryos: €1,650 – €2,400
Luteal Phase Support: €850 – €1,250
Pregnancy Confirmation: €950 – €1,400
Total Cost in Izmir: €26,500 – €39,400

IVF with PGD and Mitochondrial Replacement Therapy for Gender Selection

Istanbul

Initial Consultation and Genetic Counseling: €1,800 – €2,500
Ovarian Stimulation and Medication: €5,200 – €8,600
Egg Retrieval and Embryo Culture: €6,300 – €9,200
Sperm Collection and ICSI: €1,500 – €2,100
PGD with Mitochondrial Replacement Therapy: €9,000 – €13,500
Embryo Transfer: €3,200 – €3,800
Cryopreservation of Additional Embryos: €1,800 – €2,600
Luteal Phase Support: €1,000 – €1,400
Pregnancy Confirmation: €1,100 – €1,600
Total Cost in Istanbul: €30,900 – €44,800

Ankara

Initial Consultation and Genetic Counseling: €1,600 – €2,200
Ovarian Stimulation and Medication: €4,800 – €7,900
Egg Retrieval and Embryo Culture: €5,800 – €8,800
Sperm Collection and ICSI: €1,300 – €1,900
PGD with Mitochondrial Replacement Therapy: €8,500 – €12,800
Embryo Transfer: €3,000 – €3,500
Cryopreservation of Additional Embryos: €1,700 – €2,400
Luteal Phase Support: €900 – €1,200
Pregnancy Confirmation: €950 – €1,400
Total Cost in Ankara: €27,550 – €39,100

Izmir

Initial Consultation and Genetic Counseling: €1,500 – €2,000
Ovarian Stimulation and Medication: €5,000 – €8,200
Egg Retrieval and Embryo Culture: €6,000 – €9,000
Sperm Collection and ICSI: €1,400 – €2,000
PGD with Mitochondrial Replacement Therapy: €9,200 – €13,200
Embryo Transfer: €3,300 – €3,800
Cryopreservation of Additional Embryos: €1,750 – €2,500
Luteal Phase Support: €950 – €1,250
Pregnancy Confirmation: €1,000 – €1,500
Total Cost in Izmir: €28,900 – €41,250

IVF with PGD for Gender Selection and Embryo Glue

Istanbul

Initial Consultation and Testing: €800 – €1,200
Ovarian Stimulation and Medication: €4,200 – €6,800
Egg Retrieval and Embryo Culture: €5,000 – €7,000
Sperm Collection and ICSI: €1,000 – €1,500
PGD for Gender Selection: €6,500 – €9,500
Embryo Transfer with Embryo Glue: €2,600 – €3,100
Cryopreservation of Additional Embryos: €1,500 – €2,200
Luteal Phase Support: €700 – €1,000
Pregnancy Confirmation: €800 – €1,200
Total Cost in Istanbul: €22,100 – €32,500

Ankara

Initial Consultation and Testing: €700 – €1,100
Ovarian Stimulation and Medication: €3,800 – €6,500
Egg Retrieval and Embryo Culture: €4,500 – €6,500
Sperm Collection and ICSI: €900 – €1,400
PGD for Gender Selection: €6,000 – €9,000
Embryo Transfer with Embryo Glue: €2,300 – €2,800
Cryopreservation of Additional Embryos: €1,300 – €2,000
Luteal Phase Support: €600 – €900
Pregnancy Confirmation: €700 – €1,000
Total Cost in Ankara: €20,800 – €31,600

Izmir

Initial Consultation and Testing: €750 – €1,150
Ovarian Stimulation and Medication: €4,000 – €6,700
Egg Retrieval and Embryo Culture: €4,800 – €6,800
Sperm Collection and ICSI: €950 – €1,450
PGD for Gender Selection: €6,200 – €9,200
Embryo Transfer with Embryo Glue: €2,400 – €2,900
Cryopreservation of Additional Embryos: €1,400 – €2,100
Luteal Phase Support: €650 – €950
Pregnancy Confirmation: €750 – €1,050
Total Cost in Izmir: €21,100 – €32,450

IVF with PGD and Laser-Assisted Hatching for Gender Selection

Istanbul

Initial Consultation and Testing: €900 – €1,300
Ovarian Stimulation and Medication: €4,600 – €7,500
Egg Retrieval and Embryo Culture: €5,700 – €8,000
Sperm Collection and ICSI: €1,200 – €1,800
PGD for Gender Selection: €6,800 – €9,700
Embryo Transfer with Laser-Assisted Hatching: €2,900 – €3,500
Cryopreservation of Additional Embryos: €1,700 – €2,500
Luteal Phase Support: €900 – €1,300
Pregnancy Confirmation: €1,000 – €1,400
Total Cost in Istanbul: €25,700 – €39,000

Ankara

Initial Consultation and Testing: €800 – €1,200
Ovarian Stimulation and Medication: €4,200 – €7,200
Egg Retrieval and Embryo Culture: €5,000 – €7,500
Sperm Collection and ICSI: €1,100 – €1,700
PGD for Gender Selection: €6,500 – €9,500
Embryo Transfer with Laser-Assisted Hatching: €2,700 – €3,200
Cryopreservation of Additional Embryos: €1,500 – €2,200
Luteal Phase Support: €800 – €1,200
Pregnancy Confirmation: €850 – €1,200
Total Cost in Ankara: €24,450 – €34,700

Izmir

Initial Consultation and Testing: €850 – €1,250
Ovarian Stimulation and Medication: €4,500 – €7,300
Egg Retrieval and Embryo Culture: €5,400 – €7,800
Sperm Collection and ICSI: €1,150 – €1,750
PGD for Gender Selection: €6,600 – €9,400
Embryo Transfer with Laser-Assisted Hatching: €2,800 – €3,400
Cryopreservation of Additional Embryos: €1,600 – €2,300
Luteal Phase Support: €850 – €1,200
Pregnancy Confirmation: €950 – €1,400
Total Cost in Izmir: €24,600 – €35,550

Additional Considerations for Patients

Legal and Ethical Considerations

In Turkey, gender selection for non-medical reasons is legally permissible under specific circumstances.

However, it is essential for patients to understand the legal framework and ensure that the clinic they choose operates within the legal boundaries.

Success Rates and Clinic Selection

Patients should thoroughly research the success rates of clinics, particularly in cases involving PGD for gender selection.

Choosing a clinic with high success rates and a good track record can improve the chances of a successful outcome.

Travel and Accommodation

For international patients, additional costs such as travel, accommodation, and local transportation should be considered.

Many clinics offer medical tourism packages that include these services, which can simplify the process and potentially reduce costs.

Emotional and Psychological Support

The journey through IVF with PGD can be emotionally challenging. Patients may benefit from psychological support services offered by clinics, which can provide counseling and support throughout the process.

Insurance and Financial Planning

It is crucial for patients to consider the financial aspects of the procedure, including whether their insurance covers any part of the treatment.

Many clinics offer financing options or payment plans to help manage the cost.

Conclusion

Choosing IVF with PGD for gender selection is a significant decision that involves various medical, ethical, and financial considerations. Turkey offers a competitive option for this procedure, with a range of clinics providing high-quality care at different price points.

By understanding the detailed breakdown of costs and factors influencing the price, patients can make informed decisions and select the best clinic for their needs.

Whether in Istanbul, Ankara, or Izmir, patients can expect to find experienced professionals and state-of-the-art facilities to support their journey towards parenthood.

For those considering this path, it is essential to thoroughly research and plan, ensuring a smooth and successful experience.